RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-196a1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
qRT-PCR
Target
TGF-betaRIII
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-196a/b Mitigate Renal Fibrosis by Targeting TGF-beta Receptor 2
Year
2016
Function
"miR-196a/b silenced TGF-beta-smad signaling, decreased the expression of collagen 1 and alfa-smooth muscle action, and attenuated renal fibrosis."